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Could early palliative care before cancer surgery improve quality of life?

NCT ID NCT03436290

Symptom relief Sponsor: Vanderbilt University Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether adding a palliative care team early, before surgery, helps cancer patients manage symptoms like pain, fatigue, and anxiety. About 236 adults having certain abdominal cancer surgeries will either get usual care or usual care plus palliative support. The goal is to see if early palliative care improves physical and emotional well-being.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
palliative care intervention (behavioral)
What this could lead to
If successful, this could show that starting palliative care before surgery helps cancer patients feel better physically and emotionally.
What could go wrong
This is a relatively small study (236 people) and results may not apply to all cancer types or surgeries. The intervention is supportive, not a cure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

236 people

The number who actually took part.

Started

Mar 2018

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: adult patients (≥18 years old) scheduled for one of the following abdominal operations with intent to provide cure or durable oncologic control of malignancy: 1. Total or partial gastrectomy requiring anastomosis 2. Total or partial pancreatectomy 3. Partial hepatectomy 4. Colectomy or proctactomy if one of the following 3 conditions is also met: i) patient age is 65 years or older ii) disease is metastatic iii) disease is locally invasive requiring extensive resection 5. Radical cystectomy 6. Pelvic exenteration 7. Abdominal debulking for ovarian or endometrial carcinoma 8. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy Exclusion Criteria: 1. Non-English speaking patient 2. Residence \>150 miles away from Vanderbilt and do not visit the Nashville area regularly 3. No telephone or otherwise unwilling/unable to complete follow-ups 4. Prisoner 5. Current enrollment in a study that does not allow co-enrollment or that uses a non-pharmacologic, non-procedural intervention directed at surgical or cancer care. 6. Deaf 7. Severe prior cognitive or neurodegenerative disorder that prevents a patient from living independently at baseline 8. Inability to obtain informed consent from patient meeting all inclusion criteria for the following reasons: 1. Attending surgeon refusal 2. Patient refusal 3. Period of time between screening patient and time of operation does not allow preoperative outpatient palliative care visit. 9. Currently participating in palliative care or seeing a palliative care provider.

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Conditions

The condition(s) this trial relates to.

cancer colorectal cancer digestive system cancer endometrial cancer gastric cancer hepatocellular carcinoma malignant pancreatic neoplasm neoplasm ovarian cancer urinary bladder carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cancer

Contacts and locations

Locations

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

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