Could a common bladder drug help boys with rare birth defect?
NCT ID NCT04526353
First seen Jun 12, 2026 · Last updated Jun 19, 2026 · Updated 2 times
Summary
This study tests whether giving oxybutynin syrup early to boys aged 3-6 months with posterior urethral valves can improve bladder function. The trial includes 50 boys who have already had valve surgery. Researchers will measure bladder pressure, capacity, and compliance after 9 months of treatment to see if it works better than no treatment.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Bordeaux
RECRUITINGBordeaux, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Oxybutynin syrup
What this could lead to
If successful, this could provide an effective early treatment to improve bladder function and reduce long-term complications in boys with posterior urethral valves.
What could go wrong
This is a small Phase 2 trial with only 50 participants, so results may not apply broadly. Oxybutynin can cause side effects like dry mouth or constipation, and it may not benefit all patients.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.