New study: could a tiny camera help kids breathe better?
NCT ID NCT07383129
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares early bronchoscopy (using a thin, flexible tube with a camera to open blocked airways) against standard care (suctioning and chest therapy) for critically ill children with lung collapse that hasn't improved after 48 hours. About 36 children will be randomly assigned to one of the two groups. The goal is to see if the procedure leads to better lung re-expansion on X-rays after 5 days.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- bronchoscopy (a thin, flexible tube with a camera used to open blocked airways)
- What this could lead to
- If successful, early bronchoscopy could become a standard procedure to quickly re-inflate collapsed lungs in critically ill children, reducing hospital stays and complications.
- What could go wrong
- This is a small, early-phase trial with only 36 children, so results may not apply to all patients. Bronchoscopy carries risks like bleeding or breathing problems, and the procedure may not work better than standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 month to 13 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Radiological evidence of partial or complete lung collapse (PICU admission or during stay). Intubated, on non-invasive ventilation, or high velocity oxygen. Exclusion Criteria: * obstructive collapse from endobronchial foreign body or tissue. Extrabronchial compression (tumor, lymphadenopathy, pleural effusion/pneumothorax). Bronchoscopy contraindications: severe refractory hypoxemia, hemodynamic instability, uncorrected coagulopathy. Musculoskeletal causes (e.g., scoliosis) or congenital lung diseases (e.g., lobar emphysema).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of Medicine Cairo University
Cairo, 11562, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.