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New pill combo aims to shrink Hard-to-Treat tumors

NCT ID NCT03875287

First seen Jan 12, 2026 · Last updated May 22, 2026 · Updated 16 times

Summary

This early-phase study tests a new oral drug combination (E7727 plus decitabine) in people with advanced solid tumors that have not responded to at least two prior treatments. The main goals are to find the safest dose and to see if the drugs can slow tumor growth. Up to 35 participants will be enrolled.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

    Baltimore, Maryland, 21231, United States

  • USC Norris Comprehensive Cancer Center

    Los Angeles, California, 90089, United States

Conditions

Explore the condition pages connected to this study.