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New pill aims to fight daytime sleepiness in narcolepsy

NCT ID NCT07493265

First seen Apr 06, 2026 · Last updated May 21, 2026 · Updated 4 times

Summary

This study tests an experimental drug called E2086 in 64 adults with narcolepsy to see if it can reduce excessive daytime sleepiness. Participants will receive either the drug or a placebo for 4 weeks, and their ability to stay awake will be measured using a standard test. The goal is to find the best dose for improving alertness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AMNDX, Inc

    NOT_YET_RECRUITING

    Markham, Ontario, L3R1A3, Canada

  • ANIMA Research Center

    NOT_YET_RECRUITING

    Alken, 3570, Belgium

  • Advanced Sleep Research GmbH

    NOT_YET_RECRUITING

    Berlin, 10117, Germany

  • Alexianer St. Hedwig Kliniken Berlin GmbH

    NOT_YET_RECRUITING

    Berlin, 10115, Germany

  • Anchor Medical Research LLC

    NOT_YET_RECRUITING

    Miami, Florida, 33176, United States

  • Bogan Sleep Consultants, LLC

    RECRUITING

    Columbia, South Carolina, 29201, United States

  • CaRe Clinic - Calgary - HyperCore - PPDS

    NOT_YET_RECRUITING

    Calgary, Alberta, T2N 4L7, Canada

  • Centricity Research - CPU - Bayview

    NOT_YET_RECRUITING

    Toronto, Ontario, M4P 1P2, Canada

  • Centro Ricerche Cliniche Di Verona

    NOT_YET_RECRUITING

    Verona, 37134, Italy

  • Clinical Research Institute Stockbridge

    NOT_YET_RECRUITING

    Stockbridge, Georgia, 30291, United States

  • Corporacio Sanitaria Parc Tauli

    NOT_YET_RECRUITING

    Barcelona, 08208, Spain

  • Fondazione Istituto Neurologico Nazionale Casimiro Mondino IRCCS

    NOT_YET_RECRUITING

    Pavia, 27100, Italy

  • Future Search Trials of Neurology

    NOT_YET_RECRUITING

    Austin, Texas, 78731, United States

  • Gokeikai Osaka Kaisei Hospital

    NOT_YET_RECRUITING

    Oskaka, Osaka, 532-0003, Japan

  • Henan Provincial People's Hospital

    NOT_YET_RECRUITING

    Zhengzhou, Zhengzhou, 450003, China

  • Henry Ford Medical Center - Columbus

    NOT_YET_RECRUITING

    Novi, Michigan, 48377, United States

  • Hope Research Network Trials -6500 NW 77th CT

    NOT_YET_RECRUITING

    Medley, Florida, 33166, United States

  • Hospital Blua Sanitas Valdebebas

    NOT_YET_RECRUITING

    Madrid, 28055, Spain

  • Hospital HM Puerta del Sur

    NOT_YET_RECRUITING

    Móstoles, 28936, Spain

  • Hospital Ruber Internacional

    NOT_YET_RECRUITING

    Madrid, 28034, Spain

  • Hospital Universitario Fundacion Jimenez Diaz

    NOT_YET_RECRUITING

    Madrid, 28040, Spain

  • Hospital Universitario Virgen Macarena

    NOT_YET_RECRUITING

    Seville, 41009, Spain

  • Hospital Universitario de Donostia

    NOT_YET_RECRUITING

    Donostia / San Sebastian, 20014, Spain

  • Hospital Universitario de La Ribera

    NOT_YET_RECRUITING

    Alzira, 46600, Spain

  • Howakai Kuwamizu Hospital

    NOT_YET_RECRUITING

    Kumamuto-shi, Kumamuto, 862-0954, Japan

  • Huashan Hospital Fudan University

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200040, China

  • IRCCS Istituto dell Scienze Neurologiche di Bologna

    NOT_YET_RECRUITING

    Bologna, 40139, Italy

  • Inselspital - Universitätsspital Bern

    NOT_YET_RECRUITING

    Bern, 3010, Switzerland

  • Keimyung University Dongsan Hospital

    NOT_YET_RECRUITING

    Daegu, 42601, South Korea

  • LMU Klinikum der Universität München - Campus Grosshadern

    NOT_YET_RECRUITING

    Bayern, Muenchen, 81377, Germany

  • Meris Clinical Research-310 Oakfield Dr

    NOT_YET_RECRUITING

    Brandon, Florida, 33511, United States

  • Midwest Center for Sleep Disorders (MWCSD)

    NOT_YET_RECRUITING

    Lansing, Michigan, 48911, United States

  • Nanfang Hospital Southern Medical University

    NOT_YET_RECRUITING

    Guangdong, Guangdong, 510515, China

  • NeuroTrials Research, Inc

    NOT_YET_RECRUITING

    Atlanta, Georgia, 30328, United States

  • New Access Research & Medical Services Inc - Kendall

    NOT_YET_RECRUITING

    Miami, Florida, 33186, United States

  • RESM Respiratory and Sleep Medical Care Clinic

    NOT_YET_RECRUITING

    Yokohama, Kanagawa, 222-0033, Japan

  • Research Carolina Elite

    NOT_YET_RECRUITING

    Denver, North Carolina, 28037, United States

  • Revive Research Institute - Southfield - 23999 Northwestern Hwy

    NOT_YET_RECRUITING

    Southfield, Michigan, 48075, United States

  • SDS Clinical Trials, Inc-California-Santa Ana

    NOT_YET_RECRUITING

    Santa Ana, California, 92705, United States

  • Seoul National University Bundang Hospital

    NOT_YET_RECRUITING

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Severance Hospital Yonsei University Health System

    NOT_YET_RECRUITING

    Seoul, 03722, South Korea

  • Shandong Provincial Qianfoshan Hospital

    NOT_YET_RECRUITING

    Jinan, Jinan, 250013, China

  • Sleep & Alertness Clinic

    NOT_YET_RECRUITING

    Toronto, Ontario, M5S 3A5, Canada

  • Sleep Practitioners, LLC

    NOT_YET_RECRUITING

    Macon, Georgia, 31210, United States

  • Sleep Therapy and Research Center

    NOT_YET_RECRUITING

    San Antonio, Texas, 78229, United States

  • Somni Bene Institut für Medizinische Forschung und Schlafmedizin Schwerin GmbH

    NOT_YET_RECRUITING

    Schwerin, 19053, Germany

  • The Catholic University of Korea, St. Vincent's Hospital

    NOT_YET_RECRUITING

    Suwon, 16247, South Korea

  • The First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital)

    NOT_YET_RECRUITING

    Guangzhou, Guangzhou, 510630, China

  • The First Hospital of Jilin University

    NOT_YET_RECRUITING

    Changchun, Changchun, 130021, China

  • The Kei-Ai Corporation Aggregate Sapporo Hanazono Hospital

    RECRUITING

    Sapporo, Hokkaido, 064-0915, Japan

  • The Second Affiliated Hospital of Nanchang University - Donghu Campus

    NOT_YET_RECRUITING

    Nanchang, Nanchang, 330006, China

  • UZ Gent

    NOT_YET_RECRUITING

    Ghent, 9000, Belgium

  • Universitätsklinikum Gießen und Marburg GmbH - Standort Marburg

    NOT_YET_RECRUITING

    Marburg, 35043, Germany

  • Vitaly Clinical Research LLC

    NOT_YET_RECRUITING

    Miami, Florida, 33125, United States

  • West Ottawa Sleep Center

    NOT_YET_RECRUITING

    Ottawa, Ontario, K2C 0P7, Canada

  • Wu Lab at Johns Hopkins University

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21205, United States

  • Xuanwu Hospital Capital Medical University

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100053, China

Conditions

Explore the condition pages connected to this study.