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Can Omega-3s and a prostate drug keep Low-Risk cancer in check?
NCT ID NCT01653925
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether eating more omega-3 fatty acids (like those in fish oil) and taking a drug called dutasteride can slow the growth of low-risk prostate cancer. The 120 participants are men on active surveillance, meaning their cancer is being watched rather than treated right away. Researchers will check how these interventions affect fat levels and gene activity in the blood and prostate tissue.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dutasteride and omega-3 fatty acids
- What this could lead to
- If it works, this could point toward a way to prevent low-risk prostate cancer from progressing, potentially reducing the need for more aggressive treatments.
- What could go wrong
- This is an early-stage study with only 120 participants, so results may not apply to everyone. The dietary changes and drug may have side effects or show no clear benefit.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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120 people
The number who actually took part.
- Started
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Oct 2010
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 75 years
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Low-risk prostatic neoplasms * Candidate for active surveillance * Informed consent Exclusion Criteria: * Current fish oil supplementation * Current NSAID use
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hotel-Dieu of Quebec
Québec, Quebec, G1R 2J6, Canada
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Institute of nutraceuticals and functional food of Laval University
Québec, Quebec, G1V 0A6, Canada
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