Needles and light: a new attack on muscle pain?
NCT ID NCT07750392
First seen Aug 06, 2026 · Last updated Aug 11, 2026 · Updated 3 times
Summary
This trial tests whether dry needling and low-level laser microcurrent electrical stimulation can reduce pain and inflammation in people with acute myofascial pain syndrome in the upper trapezius muscle. Participants are randomly assigned to receive one of these treatments, a combination, or a sham procedure. The study measures changes in blood markers of inflammation and oxidative stress, along with pain intensity and neck disability, to see if these non-drug therapies offer real benefit.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Dry needling and low-level laser microcurrent electrical stimulation
- What this could lead to
- If effective, these non-drug therapies could offer a way to ease myofascial pain and reduce inflammation without medication.
- What could go wrong
- This is a small, early-stage trial, and results may not apply to everyone. The treatments may not significantly lower biomarkers or improve symptoms, and there is a risk of minor side effects like soreness or bruising.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2026
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 45 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participants must meet all of the following criteria: Adults aged 20 to 45 years. Clinical diagnosis of acute upper trapezius myofascial pain syndrome (MPS) with symptom duration of less than 1 month. Presence of at least one active myofascial trigger point in the upper trapezius muscle confirmed by physical examination according to accepted diagnostic criteria (palpable taut band, hypersensitive trigger point, reproduction of the patient's typical pain, and/or local twitch response). Moderate or greater neck pain (Numerical Pain Rating Scale \[NPRS\] ≥4). Willing and able to provide written informed consent and comply with study procedures. Exclusion Criteria: * Participants meeting any of the following criteria will be excluded: Previous dry needling or LL MCES treatment for the current episode of myofascial pain. Chronic myofascial pain syndrome (symptom duration ≥1 month). Current use of systemic corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), or other medications that may significantly influence inflammatory biomarkers within the washout period specified in the protocol. Previous surgery, fracture, or significant trauma involving the neck or shoulder region. Cervical radiculopathy, cervical myelopathy, fibromyalgia, inflammatory arthritis, or other neurological or musculoskeletal disorders that could explain the symptoms. Local skin infection, open wound, or other contraindications to dry needling or LL MCES. Bleeding disorders, anticoagulant therapy, or other contraindications to needling. Pregnancy or breastfeeding. Active malignancy, autoimmune disease, uncontrolled diabetes mellitus, acute infection, or other systemic inflammatory conditions. History of severe psychiatric illness or inability to complete study assessments. Participation in another interventional clinical trial within the previous 30 days.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Udayana University
RECRUITINGDenpasar, Bali, Indonesia
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