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Could a tiny zap to nerves cure dry mouth? new study investigates

NCT ID NCT07593495

Symptom relief Sponsor: Universidad Autonoma del Estado de Mexico Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a mild nerve stimulation technique (TENS) can help people with dry mouth produce more saliva. Researchers will measure saliva flow, acidity, and quality of life in 35 adults over one year. The goal is to find a long-term treatment beyond temporary mouth sprays or rinses.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 35 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 90 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients diagnosed with dry mouth symptoms. * Patients who wish to participate in the study. * Patients who allow saliva samples to be collected before, during, and after treatment. * Patients who allow the application of transcutaneous electrical nerve stimulation (TENS). * Patients who do not have any active oral infections. * Patients who attend all sialometry assessments and physiotherapy sessions and complete both quality of life questionnaires (initial and final). Exclusion Criteria: * Patients with any other mucosal alteration. * Patients who do not wish to participate in the study. * Patients who do not allow the collection of saliva samples. * Patients who do not allow the application of transcutaneous electrical nerve stimulation (TENS). * Patients with any infectious process in the oral cavity. * Because the study requires the use of low-frequency pulse currents, participants with pacemakers, defibrillators, hearing aids, or cochlear implants will also be excluded from the study.

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Conditions

The condition(s) this trial relates to.

Sialorrhea Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Saliva altered

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Clinic of Oral Medicine and Pathology "Orocentro", School of Dentistry, Autonomous University of the State of Mexico

    RECRUITING

    Toluca, State of Mexico, 50130, Mexico

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