New eye drop combo aims to soothe dry eyes without preservatives
NCT ID NCT06903741
First seen Nov 18, 2025 · Last updated Jun 21, 2026 · Updated 28 times
Summary
This study is testing a new preservative-free eye drop that combines trehalose, sodium hyaluronate, and NAAGA to see if it improves dry eye symptoms and quality of life over 6 months. Thirty adults with dry eye disease will use the drops daily and report their symptoms. The goal is to find a more comfortable and effective option for people who are not satisfied with current artificial tears.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Group Practice Outpatient Clinic for Specialized Medical
RECRUITINGVarna, 9002, Bulgaria
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
preservative-free eye drop containing trehalose, sodium hyaluronate, and n-acetyl-aspartyl-glutamate (NAAGA)
What this could lead to
If successful, this could provide a new, well-tolerated option for people with dry eye disease to relieve symptoms and improve daily comfort.
What could go wrong
This is a small, early-phase study with only 30 participants and no comparison group, so results may not apply broadly. The treatment aims to ease symptoms, not cure the condition.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.