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New ventilation strategy aims to cut lung complications after surgery

NCT ID NCT07186933

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 38 times

Summary

This trial tests two ways of using a breathing machine during surgery in 200 adults at high risk for lung complications. One method uses standard protective settings, while the other adjusts the machine based on each patient's lung stiffness. Researchers will track lung problems, hospital stay, ICU need, and survival to see which approach works better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital of Patras

    RECRUITING

    Pátrai, 26504, Greece

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

mechanical ventilation with lowest driving pressure

What this could lead to

If it works, this could point toward a better way to ventilate patients during surgery to reduce lung problems.

What could go wrong

This is a single-center trial with 200 participants, so results may not apply to all patients. The benefit over standard care is uncertain.

Conditions

The condition(s) this trial relates to.

aspiration pneumonitis bronchial disorder pneumothorax Pulmonary Atelectasis respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.