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Liver transplant survival: does Donor-Recipient gender matter?

NCT ID NCT07250919

Knowledge-focused Sponsor: University of Jena Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at over 1,100 liver transplant patients to see if having a donor of a different gender affects long-term survival. Researchers followed patients for up to 10 years after transplant. The goal is to understand whether gender mismatch is a risk factor, which could help improve donor-recipient matching in the future.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If clear patterns emerge, this could help doctors better match donors and recipients to improve survival after liver transplant.
What could go wrong
This is an observational study, not a trial testing a new treatment. It can show links but cannot prove cause and effect. Results may not apply to all transplant centers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,146 people

The number who actually took part.

Started

Jan 2014

Finished

Jan 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who underwent liver transplantation at who at the Ajmera transplant centre, Toronto between 2014 and 2022

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over the age of 18 Exclusion Criteria: * Cases of retransplantation * Combined organ transplantation * Cases with \>30% of missing values

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Conditions

The condition(s) this trial relates to.

chronic liver failure liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Graft survival Liver disease (alcoholic or not) Liver transplant surgery Patient survival

Contacts and locations

Locations

  • Ajmera Transplant Centre, Toronto General Hospital, University Health Network, Toronto

    Toronto, Ontario, Canada

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