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Can a heart drug help during big belly surgeries? small study tests feasibility

NCT ID NCT07000994

Knowledge-focused Sponsor: University of Hamburg-Eppendorf Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether giving the heart medication dobutamine during major abdominal surgery is practical. Researchers aimed to give dobutamine for more than 70% of the surgery time in at least 80% of patients. The study enrolled 100 adults undergoing planned major abdominal surgery. The main goal was to see if the approach is feasible, not to measure patient outcomes.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dobutamine
What this could lead to
If successful, this could show that giving dobutamine during major abdominal surgery is practical, paving the way for larger studies on whether it helps prevent heart complications.
What could go wrong
This is a small pilot study focused on feasibility, not on patient outcomes. It may not show any clear benefit, and results may not apply to other hospitals or patient groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

100 people

The number who actually took part.

Started

Jun 2025

Finished

Feb 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Consenting patients ≥18 years scheduled for elective major abdominal surgery under general anesthesia (expected surgery duration ≥ 120 minutes) * Planned continuous intraarterial blood pressure monitoring using an arterial catheter for clinical indications not related to the trial Exclusion Criteria: * Emergency surgery * Liver or kidney transplantation surgery * Status of post transplantation of kidney, liver, heart, or lung * Pregnancy * Heart rhythms other than sinus rhythm

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intraoperative myocardial depression

Contacts and locations

Locations

  • University Medical Center Hamburg-Eppendorf

    Hamburg, Free and Hanseatic City of Hamburg, 20246, Germany