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Engineered immune cells take aim at tough lung cancer

NCT ID NCT05680922

First seen Apr 07, 2026 · Last updated May 26, 2026 · Updated 8 times

Summary

This early-phase trial tests a new treatment called LB2102, which uses a patient's own immune cells (T-cells) that are modified in a lab to recognize and attack cancer cells that carry a protein called DLL3. The study includes about 41 adults with advanced small cell lung cancer or related lung cancers that have not responded to standard treatments. The main goals are to find a safe dose and to see if the treatment can shrink tumors.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10017, United States

  • Moffitt Cancer Center

    Tampa, Florida, 33612, United States

  • University of Kentucky - Markey Cancer Center

    Lexington, Kentucky, 40536, United States

Conditions

Explore the condition pages connected to this study.