Can light or laser disinfection boost dental implant success in infected sockets?
NCT ID NCT07753044
First seen Aug 07, 2026 · Last updated Aug 07, 2026
Summary
This trial tests whether photoactivated disinfection (using a light-activated dye) or Er,Cr:YSGG laser disinfection can better clean infected tooth sockets before placing an immediate dental implant, compared to standard chlorhexidine rinsing. The goal is to see which method leads to better implant stability and bone healing. Adults with a posterior tooth needing extraction and showing signs of infection may participate. The study measures implant stability, bone density changes, and pain or swelling after the procedure.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Photoactivated disinfection (toluidine blue plus light), Er,Cr:YSGG laser disinfection, or chlorhexidine irrigation, each followed by immediate implant placement
- What this could lead to
- If successful, this could identify a better way to disinfect infected tooth sockets before immediate implant placement, potentially improving implant stability and bone healing.
- What could go wrong
- This is a small early-stage trial with only 9 participants, so results may not apply broadly. The disinfection methods may not significantly outperform chlorhexidine, and there are risks of post-operative pain, swelling, or implant failure.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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9 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Feb 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients having posterior tooth/teeth indicated for extraction * Patients must exhibit radiographic evidence of infection, defined as chronic periapical pathology (radiolucency) * The extraction site should have intact surrounding alveolar bone * There must be at least 2 mm of sound bone beyond the root apex * Patients must be in overall good health and free from uncontrolled systemic conditions Exclusion Criteria: * History of radiation therapy in the head and neck region * Pregnant or lactating women * Patients on long-term antibiotic therapy, as it could influence the outcomes * Heavy Smoking: More than 10-15 cigarettes per day. * Significant bruxism or parafunctional habits affecting implant stability.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Outpatient Clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Azarita, 00203, Egypt