New program helps minority seniors fight depression and stay mobile
NCT ID NCT04545593
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a program called Positive Minds-Strong Bodies Enhanced (PMSB-E) in 427 older adults from racial, ethnic, and linguistic minority groups who had depression, anxiety, and some mobility issues. The program combined mental health support with physical exercises to help prevent disability. Researchers measured how acceptable the program was and whether it improved mood and physical function over time.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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427 people
The number who actually took part.
- Started
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Feb 2021
- Finished
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Oct 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Latino, Asian, Black, or non-Latino White adults 60+ years of age * With mild, moderate or severe depressive or anxiety symptoms. * Participants receiving medications for mental health will have this recorded and used as a covariate. * Community-dwelling participants who have some mobility limitations but are not home-bound. Exclusion Criteria: * Any specialty mental health care (therapy sessions with psychiatrist, psychologist or social worker) in the past 3 months or scheduled in the coming month. * Evidence that patient lacks capacity to consent or is cognitively impaired * Current suicidal risk (score of 4 or 5 on Paykel suicide questionnaire), whereby participant will be connected to an emergency services or specialty provider per the study emergency protocol. * Physically instability, acute or exacerbation of a chronic disease, or a neuro-musculoskeletal impairment * Severe substance abuse * Self-reported psychosis or schizophrenia * Inability to commit to 2 sessions per week
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Other studies related to the condition(s) this trial covers.
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