New brain stimulation device shows promise for Parkinson's patients

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age at the time of enrollment: 18 \~ 75; 2. Idiopathic Parkinson's disease; 3. Patient whose symptoms are not adequately controlled by best medical therapy; 4. Hoehn and Yahr stage≥2.5; 5. Patient whose symptoms are improved by at least 30% with levodopa challenge test; 6. Must be an appropriate candidate for the surgical procedures required for bilateral DBS; 7. Is willing and able to comply with all visits and study related procedures; 8. Patient understands the study requirements and the treatment procedures and provides written informed consent before any study-specific tests or procedures are performed. Exclusion Criteria: 1. Had received lesioning surgical treatment; 2. A female who is breastfeeding or of child-bearing potential with a positive urine pregnancy test or not using adequate contraception; 3. Any current drug or alcohol abuse; 4. Cognitive impairment (MMSE≦17 for primary school education or MMSE≦24 for middle school education and above); 5. Any significant psychiatric problems, including unrelated clinically significant depression; 6. Any history of craniocerebral injury, tumor, or severe cerebrovascular disease; 7. Severe brain atrophy (confirmed by CT or MRI); 8. A condition requiring or likely to require the use of diathermy; 9. Abnormal blood routine or biochemical test, coagulation dysfunction, serious abnormal liver or kidney function; 10. Uncontrolled high blood pressure, serious heart disease or serious medical or respiratory diseases; 11. Long-term of immunosuppressive or hormone therapy; 12. Other diseases requiring the stimulators; 13. A condition requiring or likely to require the use of MRI; 14. Participated in any other clinical trials within the preceding 3 months; 15. Unwilling or unable to cooperate with the implantation of DBS system; 16. Unwilling or unable to cooperate with postoperative follow-up; 17. Not considered to be applicable by the investigator.