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Simple gel may prevent Post-Filling tooth sensitivity

NCT ID NCT07540299

Symptom relief Sponsor: Postgraduate Medical Institute, Lahore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether applying a dipotassium oxalate gel before placing a filling can reduce tooth sensitivity afterward. 64 adults with sensitive tooth cavities will be randomly assigned to get the gel or standard treatment. Pain is measured at 24 hours, 7 days, and 30 days using a simple scale.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dipotassium oxalate gel
What this could lead to
If it works, this could give dentists a simple, cheap way to prevent tooth pain after fillings.
What could go wrong
This is a small, early-stage trial with only 64 people. The benefit may be small or not last long. Results may not apply to all types of fillings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

30 to 45 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals aged 30 to 45 years. * Presence of at least one tooth with a non-carious cervical lesion (Class V) with a lesion depth of ≥1 mm, requiring restorative treatment. * The NCCL must show some symptoms/signs of pre-op sensitivity on applying stimulus (i.e Air burst / ethyl chloride spray) and will be recorded. * The involved teeth must be vital and show no signs or symptoms of irreversible pulpitis or necrosis. * Subjects must be willing to provide written informed consent and commit to the study's follow-up schedule. * Subjects with fair to good oral hygiene as determined by a simplified oral hygiene index (OHI-S score ≤2). Exclusion Criteria: * Presence of carious lesions or restored teeth with existing secondary caries * Any tooth with pulpal involvement, previous root canal therapy, or periapical pathology. * Teeth with chronic periodontal disease( BPE score 3 and above.). * Individuals regularly using Desensitizing toothpastes, NSAIDs, antidepressants, or any other pain-modulating drugs that may alter sensitivity reporting.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dentin hypersensitivity, post operative sensitivity control

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Punjab Dental Hospital, Lahore

    Lahore, Punjab Province, 54000, Pakistan