Can cutting back on meat and cheese protect kidneys in diabetes?
NCT ID NCT07587918
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a diet high in acid-forming foods (like meat, cheese, and grains) affects kidney function and blood sugar in people with type 2 diabetes and chronic kidney disease. Researchers will ask 80 participants to follow either a high- or low-acid diet for 8 weeks and track changes in kidney health. They also want to see if the effects differ between White-Dutch and South-Asian Surinamese people.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age \>18 years * Presence of T2D and CKD stage G1-3a with albuminuria (\>10mg/mmol) * BMI≥ 25kg/m2 - Use of metformin on a stable dose (i.e. no changes in the last three months) * Adequate knowledge of the Dutch language to comprehend the provided study information * If incretin therapy is used, then subject must have used that for a minimum of 6 months before starting with the trial * Use of ACE inhibitors or angiotensin II receptor blokkers * Of white European Dutch or South-Asian Surinamese descent Exclusion Criteria: * Use of insulin * serum bicarbonate \< 20 mmol/L * Use of antibiotics 3 months before inclusion * Vegetarian diet - Presence of inflammatory bowel disease or other chronic inflammatory disease * Alcohol consumption of more than 14 units per week in women, or more than 21 units per week in men * Active malignancy - bariatric or other weight loss surgery in the history * patients diagnosed with eating disorders (such as bulimia nervosa, anorexia nervosa or binge-eating disorder) * HbA1c \>9% (75mmol/mol) at screening * Unmotivated or not able to adhere to a specific diet * The subject is already currently involved in a clinical trial
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Contacts and locations
Locations
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Erasmus Medical Center
Rotterdam, Netherlands
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Other studies related to the condition(s) this trial covers.
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