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Diet study reveals gene changes in weight loss responders

NCT ID NCT07012226

First seen Jan 03, 2026 · Last updated Apr 30, 2026 · Updated 14 times

Summary

This study examined how a low-calorie diet changes the activity of two genes (SIRT1 and leptin receptor) in white blood cells, and how those changes relate to heart health markers like cholesterol and triglycerides. Researchers compared people who lost a lot of weight to those who lost less weight. The goal was to understand the biological differences between high and low responders to dieting.

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Contacts and locations

Locations

  • Nutrition Clinic located in the Faculty of Nutrition Sciences, Shahid Beheshti University of Medical Sciences

    Tehran, Tehran Province, Iran

Conditions

Explore the condition pages connected to this study.