Parkinson's patients may benefit from a Plant-Based diet, new study suggests

NCT ID NCT06463769

Disease control Sponsor: University of Kiel Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether an 8-week plant-based diet, rich in fiber and low in processed foods, can improve gut bacteria and reduce inflammation in people with Parkinson's disease. Researchers will track 75 participants to see if the diet leads to healthier gut microbes and better overall health. The goal is to find a simple, low-risk way to support Parkinson's management.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance: predominantly plant-based New Nordic low-processed food (LPF) diet
What this could lead to: If successful, this could show that a simple dietary change helps manage Parkinson's symptoms by improving gut health and reducing inflammation.
What could go wrong: This is a small, early-stage trial (75 people) testing a behavioral change, not a drug. Results may not apply to everyone, and long-term adherence to the diet is uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 75 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

May 2026

An estimate. Start dates often move.

Expected to finish

Jul 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * patients with probable prodromal PD (according to predefined criteria) * patients with clinical PD with slight to moderate disease severity (Hoehn \& Yahr 1-2.5) * habitual Western Diet (≥30% of energy intake from ultra-processed food) Exclusion Criteria: * current adherence to a plant-based diet * food allergies or intolerances * significant diseases of the gastrointestinal system (e.g. celiac disease) or central nervous system, diabetes mellitus * underweight (BMI \<18.5 kg/m2) * active smoking * expected changes in medication or antibiotic treatment during the intervention

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Parkinson disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

2 sites. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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A doctor treating you

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Parkinson's patients may benefit from a Plant-Based diet, new study suggests

What the study statuses mean