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Vegan vs. omnivore: which diet leads to healthier gums?

NCT ID NCT05864768

Knowledge-focused Sponsor: G. d'Annunzio University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how diet affects gum inflammation in healthy people. Researchers compared vegans and omnivores by temporarily stopping their oral hygiene to see how their gums reacted. The goal was to understand if a vegan diet might reduce gum inflammation compared to an omnivore diet.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vegan/vegetarian diet
What this could lead to
If successful, this could help explain how diet influences gum disease risk and guide dietary recommendations for oral health.
What could go wrong
This is a small, completed study with only 36 participants, so results may not apply broadly. It does not test a treatment, only observes differences.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

Feb 2023

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Optimal systemic health conditions * Non-Smoking * Absence of cardio-vascular pathologies * Absence of pulmonary pathologies * Non-diabetic * Not pregnant * Presence of 28 teeth without prosthetic crowns or subgingival/juxtagingival interproximal restorations * FMPS \<20% at baseline * FMBS \<20% at baseline * Omnivorous or vegan diet for at least a year * Absence of periodontitis Exclusion Criteria: * Smokers * Presence of systemic pathologies * Presence of cardio-vascular disease * Presence of periodontitis * FMPS\>20% at baseline * FMBS\>20% at baseline * Pregnant women * Presence of blood pathologies * Taking medicines (hydantoins, nifedipine or cyclosporine) * Taking oral contraceptives * Bacterial, viral or fungal infections * Idiopathic gingival fibromatosis * Mucocutaneous disorders * Allergic reactions to toothpastes and mouthwashes

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontal diseases Periodontal inflammation

Contacts and locations

Locations

  • G. D'Annunzio University

    Chieti, CH, 66100, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.