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Diesel fumes may harm sense of smell and brain health, study suggests

NCT ID NCT07237958

First seen Nov 20, 2025 · Last updated Jun 22, 2026 · Updated 27 times

Summary

This study tested 40 healthy adults to see if breathing diesel exhaust changes the nose's olfactory system and thinking ability. Participants were exposed to both diesel exhaust and clean air in random order. Researchers took nose tissue samples and ran smell and cognitive tests. The goal is to understand how air pollution might raise dementia risk.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Umeå Univeristy

    Umeå, 90185, Sweden

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Diesel exhaust particles

What this could lead to

If successful, this could help explain how air pollution might contribute to dementia, pointing toward preventive strategies.

What could go wrong

This is a small, early-stage study in healthy people, not patients. It only looks at short-term effects, so it may not reflect real-world long-term risks.

Conditions

The condition(s) this trial relates to.

Alzheimer disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.