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Ultrasound of the diaphragm may predict breathing emergencies in seniors

NCT ID NCT07132268

Knowledge-focused Sponsor: Centre Hospitalier de Bethune Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
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Paused for now. It may or may not start again.
Ongoing
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Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This study looks at whether a simple, non-invasive ultrasound of the diaphragm can help predict which older adults (75+) with sudden shortness of breath will develop severe breathing failure. Researchers will measure diaphragm movement and thickness in 145 emergency patients and track who needs a breathing machine or dies from breathing problems within 7 days. The goal is to see if this quick test can guide doctors to provide faster, better care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 145 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Oct 2028

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients Aged 75 and Over Admitted to the Emergency Department for Acute Dyspnea

Ages

75 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged ≥ 75 years * Emergency admission for acute dyspnea * Requiring an emergency ultrsoung. Exclusion Criteria: * Acute respiratory distress requiring immediate invasive or non-invasive ventilation * Respiratory rate ≥ 25 breaths/min, and/or SpO2 ≤ 90% on room air, and/or PaO2 ≤ 60 mmHg * Known diaphragmatic paralysis * Patients with degenerative neuromuscular disease * State of shock: systolic blood pressure \< 90 mmHg and/or mean arterial pressure \< 65 mmHg and/or presence of skin mottling and/or CTR \> 3s * Lactate levels \> 2 mmol/L * Hypercapnic respiratory acidosis (pH \< 7.38 and PaCO2 \> 45 mmHg) * Dyspnea due to metabolic acidosis (e.g., diabetic ketoacidosis, renal failure) * Dyspnea of traumatic origin * Refusal to participate or inability to provide informed consent * Patients deprived of liberty * Patients under guardianship or curatorship

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Conditions

The condition(s) this trial relates to.

acute respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acute dyspnea Acute respiratory failure Diaphragmatic ultrasound

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    9 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Centre Hospitalier Emile Roux

    Le Puy-en-Velay, 43000, France

  • Centre Hospitalier Sud Ile-de-France

    Melun, 77000, France

  • Centre Hospitalier Victor Dupouy

    Argenteuil, 95100, France

  • Centre Hospitalier de Béthune

    Béthune, 62408, France

  • Centre Hospitalier de Douai

    Douai, 59507, France

  • Centre Hospitalier de Roubaix

    Roubaix, 59100, France

  • Centre Hospitalier de Saint-Lô

    Saint-Lô, 50000, France

  • Centre Hospitalier de Tourcoing

    Tourcoing, 59208, France

  • Centre Hospitalier de Valenciennes

    Valenciennes, 59300, France

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