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New hope for tough leukemia: experimental combo targets relapsed AML

NCT ID NCT06382168

First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 28 times

Summary

This study tests a new two-drug combination for adults with acute myeloid leukemia (AML) that has come back or not responded to prior treatments. The drugs, DFP-10917 and venetoclax, are given together to see if they are safe and can shrink or eliminate leukemia cells. About 39 participants will receive the treatment in two phases, first to find the best dose and then to measure how well it works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center

    RECRUITING

    Winston-Salem, North Carolina, 27157, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCI Chao Family Comprehensive Cancer Center

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Vermont Cancer Center

    RECRUITING

    Burlington, Vermont, 05401, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Virginia Cancer Center

    RECRUITING

    Charlottesville, Virginia, 22911, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.