Sugar water injection may fix leaky lungs after surgery
NCT ID NCT07548047
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
After lung surgery, some patients have a persistent air leak that requires a chest tube for days. This study tests whether injecting a sugar water solution (dextrose) through the tube can seal the leak faster than standard drainage alone. About 80 adults with a stubborn air leak will be randomly assigned to get dextrose or usual care. The goal is to see if dextrose shortens the time the leak lasts and reduces hospital stay.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dextrose solution (sugar water)
- What this could lead to
- If it works, this could offer a cheap, simple way to seal air leaks after lung surgery, reducing time with a chest tube and hospital stay.
- What could go wrong
- This is a small, early-phase trial (80 people) at one center. Dextrose may not work better than standard care, and risks like fever or infection are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jun 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients who have undergone lung resection * Persistent post-operative air leak \>24 hours after surgery with air leak \>20 mL/min Exclusion Criteria: * pregnant patients * incarcerated patients * patients with early post-operative complications * hemodynamic instability * need for mechanical ventilator support * high volume chest tube output (\>750 mL over 24h)
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.