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Which painkiller combo works best after hernia repair?

NCT ID NCT07194694

Symptom relief Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether adding dexmedetomidine or ketamine to a standard numbing medicine (bupivacaine) improves pain control after inguinal hernia surgery. Sixty adults received one of three injections into the abdominal wall just before waking up. Researchers measured pain scores and blood pressure over the first 12 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexmedetomidine, ketamine, and bupivacaine
What this could lead to
If one additive works better, it could mean longer pain relief after hernia surgery with fewer side effects.
What could go wrong
This is a small, single-center trial (60 people). Results may not apply to everyone, and neither additive may prove clearly better than bupivacaine alone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

60 people

The number who actually took part.

Started

Oct 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing unilateral inguinal hernioplasty of ASA I or II. * Age group: 18-60 years old. Exclusion Criteria: * Patient refusal. * known allergy to any of the used drugs * ASA III or above * Coagulation disorders and thrombocytopenia * Body mass index (BMI) \>30 * Infection at needle insertion site * Patients undergoing bilateral inguinal hernioplasty

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Postoperative pain relief

Contacts and locations

Locations

  • Ain Shams University Hospitals

    Cairo, Egypt

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