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New combo therapy aims to tame AML without harsh chemo

NCT ID NCT07014462

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 31 times

Summary

This study tests whether adding the anti-inflammatory drug dexamethasone to a standard low-intensity therapy (venetoclax plus another chemo drug) is safe and tolerable for adults with newly diagnosed acute myeloid leukemia (AML) who cannot have intensive chemotherapy. About 20 participants will receive the combination over six cycles. The main goal is to check for side effects, with secondary goals of tracking quality of life and treatment response.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

Conditions

Explore the condition pages connected to this study.