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New pill may help teens regrow hair lost to alopecia

NCT ID NCT07133308

Disease control Sponsor: Sun Pharmaceutical Industries, Inc. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an oral drug called deuruxolitinib in teenagers aged 12 to 17 who have lost at least half their scalp hair due to alopecia areata. The goal is to see if the drug can safely regrow hair. Participants will be randomly assigned to receive either the drug or a placebo for a period, followed by an open-label phase where everyone can get the drug.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
deuruxolitinib (an oral tablet that targets inflammation)
What this could lead to
If successful, this could provide a new treatment option for teenagers with severe alopecia areata, helping regrow significant scalp hair.
What could go wrong
This is still an experimental drug; it may not work for everyone, and side effects are possible. The trial is relatively small and early-stage for this age group.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 355 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

May 2028

An estimate. End dates often move.

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

12 to 17 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Clinical presentation compatible with alopecia areata with a current episode lasting at least 6 months and not exceeding 10 years. * Between 12 to \<18 years of age * At least 50% scalp hair loss, as defined by a Severity of Alopecia Tool (SALT) score ≥50. * Willing to comply with the study visits and requirements of the study protocol Exclusion Criteria: * Active scalp inflammation, psoriasis, or seborrheic dermatitis requiring topical treatment to the scalp, significant trauma to the scalp, or other scalp condition that may interfere with the SALT assessment, or untreated actinic keratosis at Screening and/or Baseline * Treatment with other medications or agents within 28 days of Baseline or during the study that may affect hair regrowth or immune response. * Females who are nursing, pregnant, or planning to become pregnant while in the study, and for 30 days after last dose of study drug. * Clinically significant medical condition, psychiatric disease, or social condition, as determined by the Investigator, that may unfavorably alter the risk-benefit of study participation, adversely affect study compliance, or confound interpretation of study results.

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Conditions

The condition(s) this trial relates to.

alopecia areata

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alopecia areata

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    64 sites in 2 countries. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Advance Research Center, Llc

    RECRUITING

    Miami, Florida, 33183, United States

  • Alberta Dermasurgery Centre

    RECRUITING

    Edmonton, Alberta, T6G 1C3, Canada

  • All X Ray Diagnostic Services Corp

    RECRUITING

    Miami, Florida, 33126, United States

  • Asr, Llc

    RECRUITING

    Boise, Idaho, 83702, United States

  • Austin Institute For Clinical Research Inc.

    RECRUITING

    Pflugerville, Texas, 78660, United States

  • Avacare - Cct Research - Center For Dermatology And Plastic Surgery

    RECRUITING

    Scottsdale, Arizona, 85260, United States

  • Avacare - Cct Research - Springville Dermatology

    RECRUITING

    Springville, Utah, 84663, United States

  • Barroso Medical Services Llc

    RECRUITING

    Miami Lakes, Florida, 33014, United States

  • Boeson Research Mso

    RECRUITING

    Missoula, Montana, 59804, United States

  • Care Clinic Ltd.

    RECRUITING

    Red Deer, Alberta, T4P 1K4, Canada

  • Center For Dermatology Clinical Research Inc.

    RECRUITING

    Fremont, California, 94538, United States

  • Cleaver Medical Group Dermatology

    RECRUITING

    Cumming, Georgia, 30040, United States

  • Colorado Medical Research Center

    RECRUITING

    Denver, Colorado, 80210, United States

  • D&H Doral Research Center

    RECRUITING

    Doral, Florida, 33122, United States

  • Darst Dermatology

    RECRUITING

    Charlotte, North Carolina, 28277, United States

  • Dawes Fretzin Clinical Research Group Llc.

    RECRUITING

    Indianapolis, Indiana, 46250, United States

  • Delricht Research - Smyrna

    RECRUITING

    Smyrna, Tennessee, 37167, United States

  • Denova Research

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Dermatologists Of Southwest Ohio

    RECRUITING

    Mason, Ohio, 45040, United States

  • Dermatology Associates Of Plymouth Meeting

    RECRUITING

    Plymouth Meeting, Pennsylvania, 19462, United States

  • Dermatology Research Associates

    RECRUITING

    Los Angeles, California, 90045, United States

  • Dermatology Research Institute (Calgary)

    RECRUITING

    Calgary, Alberta, T2J 7E1, Canada

  • Dermatology Treatment And Research Center - Dallas

    RECRUITING

    Dallas, Texas, 75230, United States

  • Dermatology Trial Associates

    RECRUITING

    Bryant, Arkansas, 72022, United States

  • Dr. S. K. Siddha Medicine Professional Corporation

    RECRUITING

    Newmarket, Ontario, L3Y 5G8, Canada

  • Ds Research - Indiana

    RECRUITING

    Clarksville, Indiana, 47129, United States

  • Ds Research - Kentucky

    RECRUITING

    Louisville, Kentucky, 40241, United States

  • Enverus Medical Research

    RECRUITING

    Surrey, British Columbia, V3V 0C6, Canada

  • Facet Dermatology

    RECRUITING

    Toronto, M4E 1R7, Canada

  • Florida International Medical Research

    RECRUITING

    Miami, Florida, 33134, United States

  • Florida Pharmaceutical Research And Associates, Inc.

    RECRUITING

    Miami, Florida, 33143, United States

  • Georgia Skin & Cancer Clinic

    RECRUITING

    Savannah, Georgia, 31419, United States

  • Ilumina Medical Research Llc

    RECRUITING

    Kissimmee, Florida, 34744, United States

  • International Clinical Research Us Llc - Sanford

    RECRUITING

    Sanford, Florida, 32771, United States

  • Jordan Valley Dermatology

    RECRUITING

    South Jordan, Utah, 84095, United States

  • Kern Research Inc.

    RECRUITING

    Bakersfield, California, 93301, United States

  • Kirk Barber Research

    RECRUITING

    Calgary, Alberta, T2G 1B1, Canada

  • L&C Professional Medical Research Institute

    RECRUITING

    Miami, Florida, 33144, United States

  • Lenus Research & Medical Group Llc.

    RECRUITING

    Sweetwater, Florida, 33172, United States

  • Lynderm Research Inc.

    RECRUITING

    Markham, Ontario, L3P 1X3, Canada

  • Medical Arts Health Research Group - Kelowna

    RECRUITING

    Kelowna, British Columbia, V1Y4N7, Canada

  • Medisearch Clinical Trials

    RECRUITING

    Saint Joseph, Missouri, 64506, United States

  • Millennium Medical Research Llc

    RECRUITING

    Miami, Florida, 33126, United States

  • National Eagle Research, Llc

    RECRUITING

    Lynnwood, Washington, 98036, United States

  • Nexus Research Llc

    RECRUITING

    Pompano Beach, Florida, 33063, United States

  • North Texas Center For Clinical Research

    RECRUITING

    Frisco, Texas, 75034, United States

  • Oakland Hills Dermatology

    RECRUITING

    Auburn Hills, Michigan, 48326, United States

  • Palmtree Clinical Research

    RECRUITING

    Palm Springs, California, 92262, United States

  • Paradigm Clinical Research - San Diego

    RECRUITING

    San Diego, California, 92108, United States

  • Paradigm Clinical Research - Wheat Ridge

    RECRUITING

    Wheat Ridge, Colorado, 80033, United States

  • Pediatric Skin Research Llc

    RECRUITING

    Miami, Florida, 33156, United States

  • Research Toronto

    RECRUITING

    Toronto, Ontario, M4W 2N4, Canada

  • Revival Research Institute, Llc - Cary, Nc

    RECRUITING

    Cary, North Carolina, 27511, United States

  • Revival Research Institute, Llc - Troy, Mi

    RECRUITING

    Troy, Michigan, 48084, United States

  • Schweiger Dermatology & Allergy - Verona

    RECRUITING

    Verona, New Jersey, 07044, United States

  • Skin Care Physicians Of Georgia

    RECRUITING

    Macon, Georgia, 31217, United States

  • Skin Care Research, Llc - Hollywood

    RECRUITING

    Hollywood, Florida, 33021, United States

  • Skin Specialists, Pc

    RECRUITING

    Omaha, Nebraska, 68144, United States

  • Texas Dermatology And Laser Specialists

    RECRUITING

    San Antonio, Texas, 78218, United States

  • Total Skin And Beauty Dermatology Center

    RECRUITING

    Birmingham, Alabama, 35203, United States

  • Tribe Clinical Research, Llc

    RECRUITING

    Greenville, South Carolina, 29607, United States

  • U.S. Dermatology Partners - Rockville

    RECRUITING

    Rockville, Maryland, 20850, United States

  • Valencia Medical & Research Center

    RECRUITING

    Miami, Florida, 33174, United States

  • Vitality Clinical Trials

    RECRUITING

    Woodbury, New York, 11797, United States

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Other studies related to the condition(s) this trial covers.