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New hope for Tough-to-Treat depression: experimental Add-On drug enters final testing

NCT ID NCT06786624

Summary

This study is testing whether adding an experimental drug called NBI-1065845 to a person's current antidepressant medication helps reduce depression symptoms more effectively. It involves 200 adults with moderate-to-severe depression who haven't gotten enough relief from their current antidepressant alone. Participants will continue taking their regular antidepressant while receiving either the experimental add-on drug or a placebo for 8 weeks to compare results.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Neurocrine Clinical Site

    RECRUITING

    Little Rock, Arkansas, 72204, United States

  • Neurocrine Clinical Site

    COMPLETED

    Garden Grove, California, 92844, United States

  • Neurocrine Clinical Site

    RECRUITING

    Orange, California, 92866, United States

  • Neurocrine Clinical Site

    RECRUITING

    Pico Rivera, California, 90660, United States

  • Neurocrine Clinical Site

    RECRUITING

    San Diego, California, 92103, United States

  • Neurocrine Clinical Site

    RECRUITING

    Upland, California, 91786, United States

  • Neurocrine Clinical Site

    RECRUITING

    Hollywood, Florida, 33024, United States

  • Neurocrine Clinical Site

    RECRUITING

    Maitland, Florida, 32751, United States

  • Neurocrine Clinical Site

    RECRUITING

    Boston, Massachusetts, 02116, United States

  • Neurocrine Clinical Site

    SUSPENDED

    Watertown, Massachusetts, 02472, United States

  • Neurocrine Clinical Site

    RECRUITING

    Mount Kisco, New York, 10549, United States

  • Neurocrine Clinical Site

    RECRUITING

    Avon Lake, Ohio, 44012, United States

  • Neurocrine Clinical Site

    COMPLETED

    Westlake, Ohio, 44145, United States

  • Neurocrine Clinical Site

    RECRUITING

    Dallas, Texas, 75251, United States

  • Neurocrine Clinical Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Neurocrine Clinical Site

    WITHDRAWN

    Richmond, Texas, 77407, United States

  • Neurocrine Clinical Site

    SUSPENDED

    The Woodlands, Texas, 77381, United States

  • Neurocrine Clinical Site

    RECRUITING

    Everett, Washington, 98201, United States

Conditions

Explore the condition pages connected to this study.