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Brain study reveals how depression meds and therapy rewire symptoms

NCT ID NCT07488910

First seen May 01, 2026 · Last updated Jun 19, 2026 · Updated 5 times

Summary

This study looks at how different treatments for depression—medication, talk therapy, or both—change the way symptoms like sadness, sleep problems, and low energy are connected. Researchers will track 90 adults with mild to moderate depression using smartphone surveys to see which treatment works best for which symptom patterns. The goal is to help doctors choose the right treatment for each person.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Clinical Psychology and Psychotherapy

    Frankfurt, 60486, Germany

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Psychiatry and Psychotherapy

    Marburg, 35039, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Department of Psychiatry, Psychosomatics and Psychotherapy

    Frankfurt, 60528, Germany

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.