New dental membrane aims to keep your smile intact after tooth pull
NCT ID NCT07334067
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a special membrane placed in the tooth socket right after a front tooth is removed, along with a bone graft, to help the gum and bone heal in a way that keeps the area looking natural. Forty adults who need a front tooth pulled and cannot get an immediate implant will be randomly assigned to have the wound either left open or stitched closed. Researchers will measure how quickly the gum heals and how much bone forms over three months using photos and 3D X-rays.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dental prosthesis membrane (PCL membrane) and bone graft material (Bio-oss)
- What this could lead to
- If it works, this could offer a better way to preserve the shape of the gums and bone after a front tooth is pulled, making future dental implants or bridges look more natural.
- What could go wrong
- This is a small, early-stage study with only 40 participants and no blinding, so results may not apply to everyone. The membrane and graft are not new, so the benefit over existing methods may be small.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * 1: Age ≥18 years old 2: The affected teeth did not have the conditions for immediate implant placement: thin gingival biotype, labial bone plate thickness \<1 mm, the labial bone plate was missing, the distance between the labial bone plate crest and the cemento-enamel junction\>3 mm 3: No systemic diseases and good oral hygiene 4: Be willing to receive treatment and regular follow-up and review, and signed the informed consent Exclusion Criteria: * 1: Uncontrolled systemic diseases, such as heart, liver and kidney diseases, systemic infections, diabetes, etc 2: Women who are pregnant or lactating 3: Taking bisphosphonates, glucocorticoids and other drugs that affect bone metabolism for a long time or within 5 years 4: Patients receiving oral and maxillofacial radiotherapy in the past five years 5: Patients suffering uncontrolled periodontal disease
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Stomatology Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310000, China
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