Dental implant design may affect bone health, new study suggests
NCT ID NCT05859113
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how the type of connection in dental implants affects bone loss around them. Researchers will compare two types of connections (conical vs. hexagonal) in 42 people who are missing one tooth. They will measure bone levels, bacteria, and inflammation over time to see which connection works better.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 42 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2023
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 75 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * One missing tooth in the premolar or molar area with both opposing and adjacent teeth (mesial and distal). Exclusion Criteria: * One-stage bone augmentation. * Uncontrolled type 1 or 2 diabetes (HgA1c\>8). * Known auto-immune or inflammatory disease. * Severe hematologic disorders, such as hemophilia or leukemia. * Local or systemic infection that may compromise normal healing (e.g., extensive periapical pathology). * Liver or kidney dysfunction/failure. * Currently receiving cancer treatment or within 18 months from completion of radio- or chemotherapy. * Long-term history of oral bisphosphonates use (i.e., 10 years or more). * History of intravenous bisphosphonates. * Long-term (\>3 months) history of antibiotics or drugs known to alter the inflammation and/or immunological system 3 months before inclusion. * Severe osseous diseases (e.g., Paget disease of bone). * Pregnant women or nursing mothers. * Not able or not willing to follow instructions related to the study procedures.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Universidad de Granada
Granada, Granada, 18071, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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