Which filling technique is gentler on tooth nerves?
NCT ID NCT07694661
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This trial tests three different ways of placing resin composite fillings in deep cavities to see which one causes the least irritation to the tooth's nerve (pulp). Adults with deep decay in their molars will receive one of the filling techniques, and researchers will measure inflammation in the fluid around the tooth and any pain afterward. The goal is to find a method that keeps the pulp healthy and reduces discomfort after treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sonic Fill bulk fill resin composite
- What this could lead to
- If successful, this trial could identify a filling technique that reduces post-operative pain and inflammation, improving dental care for deep cavities.
- What could go wrong
- This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The findings are based on inflammatory markers and pain scores, not long-term outcomes.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
30 people
The number who actually took part.
- Started
-
Feb 2025
- Finished
-
Jan 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
21 to 50 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Both genders. * Systemically healthy patients. * Good oral hygiene. * Available for follow-up appointments. * Asymptomatic permanent molars with deep occlusal caries ICDAS 5 or 6 carious lesions and healthy periodontium, in normal occlusion with no previous restorations related to the teeth and vital with a positive response to cold testing. Exclusion Criteria: * Vulnerable populations. * Tobacco users. * Medically compromised patients, such as those with diabetes or medications affecting salivary flow were excluded. * Teeth with prior endodontic treatment, periodontal pockets over 3 mm, or any dental/periodontal therapy within the past 12 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ain shams university
Giza, 3235142, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.