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Ultrasound clues could predict dangerous dengue

NCT ID NCT07621848

Knowledge-focused Sponsor: National Center for Gastroentestinal and Liver Disease Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at 150 people with dengue fever to see if abdominal ultrasound findings, like gallbladder thickening or fluid in the belly, are linked to low platelet counts—a sign of severe disease. Researchers reviewed medical records and ultrasound images to find patterns that might help doctors spot serious cases early. The goal is to make ultrasound a practical tool for managing dengue in places where resources are limited.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help doctors use ultrasound to identify dengue patients at risk of severe complications earlier, especially in areas with limited resources.
What could go wrong
This is a small, retrospective study that only looks back at existing records, so it cannot prove cause and effect. The findings may not apply to all dengue patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

150 people

The number who actually took part.

Started

Jul 2024

Finished

Feb 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of patients with confirmed dengue infection who presented to healthcare facilities in Kassala, Sudan, between July 2024 and February 2025. All included patients had undergone abdominal ultrasonography as part of their clinical evaluation. Demographic, clinical, laboratory, and imaging data were retrospectively collected and analyzed to assess the relationship between ultrasound findings and disease severity.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with laboratory-confirmed dengue infection (NS1 positive) * Patients who underwent abdominal ultrasonography during the course of illness * Availability of complete clinical, laboratory (including platelet count), and ultrasound data * Patients of all age groups and both sexes Exclusion Criteria: * Patients without confirmed dengue diagnosis * Patients with incomplete or missing clinical, laboratory, or ultrasound records * Patients with pre-existing hepatic, hematologic, or abdominal conditions that may affect ultrasound findings (e.g., chronic liver disease, malignancy) * Poor-quality or non-interpretable ultrasound images

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Conditions

The condition(s) this trial relates to.

dengue disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dengue fever

Contacts and locations

Locations

  • Kassala Advanced Diagnostic Center

    Kassala, Sudan

More trials for these conditions

Other studies related to the condition(s) this trial covers.