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Which filling works best for deep cavities? new study aims to find out

NCT ID NCT06637605

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests three types of dental fillings—high-viscosity glass ionomer, bulk-fill composite, and conventional composite—in 110 adults with deep cavities. The goal is to see which material performs best and causes less irritation to the tooth's nerve. Participants are healthy adults with good oral hygiene and deep cavities that don't reach the pulp.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental restorative materials (high-viscosity glass ionomer, bulk-fill composite, conventional composite)
What this could lead to
If successful, this could show that high-viscosity glass ionomer is a better option for deep cavities, reducing tooth sensitivity and improving restoration longevity.
What could go wrong
This is a small, early-stage study with only 110 participants, so results may not apply to everyone. Different materials may still cause pulp irritation or fail over time.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

110 people

The number who actually took part.

Started

Feb 2023

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The characteristics of the teeth were recorded before the restorative procedures. Periapical radiographs were used to determine the status and extent of caries and any potential periodontal or periapical pathology that might require endodontic treatment. The treated teeth were vital, asymptomatic, and in occlusal contact. As a result of the clinical and radiographic evaluations, teeth with deep caries lesions according to the ESE (European Society of Endodontology) criteria or those with radiographically reaching ¾ of the dentin but with a hard dentin zone between the caries and the pulp were included in the study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Systemically healthy patients aged 18 and over * Patients with good oral hygiene. * Vital teeth are to be included in the study. * The presence of an antagonist and a contact tooth for the tooth to be restored. * Teeth with deep caries lesions or radiographically reaching ¾ of the dentin but with a hard dentin region between the caries and the pulp according to ESE (European Society of Endodontology) criteria. Exclusion Criteria: * Patients with a history of bruxism and periodontal disease * Patients under 18 years of age * Spontaneous pain in the tooth to be restored * Intense carious lesion reaching the entire thickness of the dentin according to ESE (European Society of Endodontology) criteria * Observation of mechanical perforation during caries cleaning * Patients suspected of pregnancy or pregnant

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • 53020

    Rize, 53020, Turkey (Türkiye)

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