Which filling works best for deep cavities? new study aims to find out
NCT ID NCT06637605
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests three types of dental fillings—high-viscosity glass ionomer, bulk-fill composite, and conventional composite—in 110 adults with deep cavities. The goal is to see which material performs best and causes less irritation to the tooth's nerve. Participants are healthy adults with good oral hygiene and deep cavities that don't reach the pulp.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dental restorative materials (high-viscosity glass ionomer, bulk-fill composite, conventional composite)
- What this could lead to
- If successful, this could show that high-viscosity glass ionomer is a better option for deep cavities, reducing tooth sensitivity and improving restoration longevity.
- What could go wrong
- This is a small, early-stage study with only 110 participants, so results may not apply to everyone. Different materials may still cause pulp irritation or fail over time.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
110 people
The number who actually took part.
- Started
-
Feb 2023
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The characteristics of the teeth were recorded before the restorative procedures. Periapical radiographs were used to determine the status and extent of caries and any potential periodontal or periapical pathology that might require endodontic treatment. The treated teeth were vital, asymptomatic, and in occlusal contact. As a result of the clinical and radiographic evaluations, teeth with deep caries lesions according to the ESE (European Society of Endodontology) criteria or those with radiographically reaching ¾ of the dentin but with a hard dentin zone between the caries and the pulp were included in the study.
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Systemically healthy patients aged 18 and over * Patients with good oral hygiene. * Vital teeth are to be included in the study. * The presence of an antagonist and a contact tooth for the tooth to be restored. * Teeth with deep caries lesions or radiographically reaching ¾ of the dentin but with a hard dentin region between the caries and the pulp according to ESE (European Society of Endodontology) criteria. Exclusion Criteria: * Patients with a history of bruxism and periodontal disease * Patients under 18 years of age * Spontaneous pain in the tooth to be restored * Intense carious lesion reaching the entire thickness of the dentin according to ESE (European Society of Endodontology) criteria * Observation of mechanical perforation during caries cleaning * Patients suspected of pregnancy or pregnant
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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53020
Rize, 53020, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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