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Brain scans reveal how cravings hijack your choices

NCT ID NCT06440577

Knowledge-focused Sponsor: Rutgers, The State University of New Jersey Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how strong desires (cravings) change the way people make decisions. Researchers will use brain scans and decision-making tasks to see how craving for opioids or a specific snack affects what people are willing to pay for items. The study involves 160 adults, including people being treated for opioid use disorder and healthy volunteers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 160 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * At least 18 years of age * Willingness to follow study requirements, as evidenced by an ability to provide written informed consent and read, understand, and complete the study procedures * Minimum of 6th grade reading level Additional inclusion criteria for participants with OUD: * Primary diagnosis of OUD encompassing heroin and/or painkiller use * Receiving medications for OUD treatment on an outpatient basis * At least 12-month history of opioid use Exclusion Criteria: * Unable to speak or read English * Active psychosis or mania * Current or past schizophrenia diagnosis * History of intellectual disability or developmental or neurological disorder, seizures or epilepsy, or loss consciousness lasting more than 30 minutes * Severe medical conditions requiring hospitalization or that, in the opinion of the study staff could compromise study participation * MRI contraindications (claustrophobia, nonremovable piercings, certain metal in the body etc.) or pregnancy Additional exclusion criteria for community control participants: * Positive urine drug screen * Current or past problematic substance use other than nicotine, and alcohol abuse confined to college or military service * Current or past bipolar disorder diagnosis * Use of central nervous system medications within the past 6 weeks (e.g., antidepressants, Ritalin)

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Conditions

The condition(s) this trial relates to.

opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Decision making

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Rutgers, The State University of New Jersey

    RECRUITING

    Piscataway, New Jersey, 08854, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.