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Dietary choice may unlock type 2 diabetes remission without drugs

NCT ID NCT05710900

Disease control Sponsor: University of British Columbia Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial tests whether a low-calorie or low-carbohydrate diet can help people with type 2 diabetes achieve remission—meaning blood sugar returns to normal without medication. One hundred adults aged 20–80 with type 2 diabetes and a BMI of 27 or higher will follow a structured diet program supported by pharmacists and dietitians. The study will compare how well participants stick to each diet and how many achieve remission over one year.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a low-calorie or low-carbohydrate dietary intervention
What this could lead to
If successful, this could show that structured dietary programs can help many people with type 2 diabetes achieve remission without medication.
What could go wrong
This is a small, early-stage trial with only 100 participants. Dietary adherence can be challenging, and results may not apply to everyone with type 2 diabetes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2023

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 20-80 years old * Diagnosed with T2D by a physician, * HbA1c ≥ 6.0%, * Body Mass Index ≥27 kg/m2 and * No contraindications or dietary restrictions to following a low-carbohydrate/low-calorie diet. Exclusion Criteria: * History of heart disease, heart attack, heart failure, stroke or coronary artery disease within the previous 2 years, * any current unstable cardiovascular disorder, * history of liver disease, * history of kidney disease with eGFR \<30 mls/min/1.73 m2, * history of neurological disease, * previous bariatric surgery, * weight loss (≥5%) within the last six months * currently pregnant or lactating, or planning on becoming pregnant within the next 12 months, * history of cancer within the previous 5 years, * dietary restrictions or allergies that would inhibit adherence to the intervention diet, * history of eating disorders, * moderate or severe depression, anxiety or mental health condition that impacts daily life, * currently following a low-carbohydrate or low-calorie diet, and * unable to access the Internet (for communication with research team and RD).

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Conditions

The condition(s) this trial relates to.

type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Type 2 diabetes

Contacts and locations

Locations

  • University of British Columbia Okanagan

    Kelowna, British Columbia, V1V 3G1, Canada

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