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Can less be more? study tests cutting back antibiotics in sepsis

NCT ID NCT01626612

First seen May 12, 2026 · Last updated May 20, 2026 · Updated 4 times

Summary

This study looked at whether doctors can safely reduce or narrow the antibiotics given to patients with severe sepsis once the exact germ is identified. 120 adults in intensive care units were randomly assigned to either continue the original broad antibiotics or switch to a more targeted treatment. The goal was to see if the targeted approach kept patients safe without increasing hospital stays or deaths, while also reducing the risk of creating superbugs.

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Contacts and locations

Locations

  • Assistance Publique Hopitaux de Marseille

    Marseille, 13354, France

Conditions

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