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New hope for vulnerable patients: drug trial targets parainfluenza lung infections

NCT ID NCT03808922

First seen May 19, 2026 · Last updated May 20, 2026 · Updated 1 time

Summary

This study tests an experimental drug called DAS181 in people with weakened immune systems who have a parainfluenza infection in their lungs. The goal is to see if the drug helps them breathe without extra oxygen and improves survival. About 274 participants will be randomly assigned to receive DAS181 or a placebo. The study also includes a smaller group of patients with severe COVID-19.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

  • Asan Medical Center

    TERMINATED

    Seoul, Gyeonggi-do, 05505, South Korea

  • Baylor College of Medicine

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

  • Beth Israel Deaconess Medical Center

    WITHDRAWN

    Boston, Massachusetts, 02215, United States

  • Brigham and Women's Hospital

    RECRUITING

    Boston, Massachusetts, 02115, United States

  • Children's Hospital Colorado

    WITHDRAWN

    Aurora, Colorado, 80045, United States

  • Cincinnati Children's Hospital Medical Center

    RECRUITING

    Cincinnati, Ohio, 45267, United States

  • City of Hope cancer Center

    RECRUITING

    Duarte, California, 91010, United States

  • Cook Children's

    TERMINATED

    Forth Worth, Texas, 76104, United States

  • Duke University

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

    Contact

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

  • Fred Hutchinson Cancer Research Center

    RECRUITING

    Seattle, Washington, 98109, United States

  • Froedtert Medical College Pulmonary Clinic

    RECRUITING

    Milwaukee, Wisconsin, 53266, United States

    Contact

    Contact

  • Houston Methodist Hospital

    WITHDRAWN

    Tampa, Florida, 33612, United States

  • Houston Methodist Hospital

    WITHDRAWN

    Houston, Texas, 77030, United States

  • Hôpital Henri Mondor

    TERMINATED

    Créteil, Île-de-France Region, 94010, France

  • Kent Hospital

    COMPLETED

    Warwick, Rhode Island, 02886, United States

  • Louisiana State University

    COMPLETED

    Shreveport, Louisiana, 71103, United States

  • Loyola University Medical Center

    WITHDRAWN

    Maywood, Illinois, 60153, United States

  • MD Anderson

    RECRUITING

    Houston, Texas, 77030, United States

  • Mayo Clinic Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

  • Memorial Sloan Kettering Cancer Center

    WITHDRAWN

    New York, New York, 10065, United States

  • National Cheng Kung University Hospital

    TERMINATED

    Tainan, Tainan, Taiwan

  • National Taiwan University Hospital

    TERMINATED

    Zhongzheng, Taipei City, 10002, Taiwan

  • Novant Health

    WITHDRAWN

    Winston-Salem, North Carolina, 27103, United States

  • Oregon Health & Science University

    WITHDRAWN

    Portland, Oregon, 97239, United States

  • Peter MacCallum Cancer Centre

    TERMINATED

    Melbourne, Victoria, 3050, Australia

  • Prince of Wales Hospital

    TERMINATED

    Shatin, New Territories, Hong Kong

  • Rigshospitalet

    TERMINATED

    Copenhagen, 2100, Denmark

  • Royal Melbourne Hospital

    TERMINATED

    Melbourne, Victoria, 3050, Australia

  • Samsung Medical Center

    TERMINATED

    Seoul, Gyeonggi-do, 06351, South Korea

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

  • Seoul National University Bundang Hospital

    TERMINATED

    Seongnam-si, Gyeonggi-do, 13620, South Korea

  • Seoul National University Hospital

    TERMINATED

    Seoul, Gyeonggi-do, 03080, South Korea

  • Shanghai Pulmonary Hospital

    TERMINATED

    Yangpu, Shanghai Municipality, 200433, China

  • Shulan (Hangzhou) Hospital co., LTD

    TERMINATED

    Hangzhou, Zhejiang, China

  • St. Elizabeth Youngstown Hospital

    WITHDRAWN

    Youngstown, Ohio, 44501, United States

  • Sylvester Comprehensive Cancer Center, University of Miami Health System

    RECRUITING

    Miami, Florida, 33136, United States

  • Texas Health

    COMPLETED

    Forth Worth, Texas, 76104, United States

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    TERMINATED

    Seoul, Gyeonggi-do, 06591, South Korea

  • The Cleveland Clinic Foundation

    WITHDRAWN

    Cleveland, Ohio, 44106, United States

  • The First Affiliated Hospital, Zhejiang University School of Medicine

    TERMINATED

    Hangzhou, Zhejiang, China

  • The Johns Hopkins Hospital

    WITHDRAWN

    Baltimore, Maryland, 21205, United States

  • The Lindner Center- The Christ Hospital

    WITHDRAWN

    Cincinnati, Ohio, 45219, United States

  • The Wesley Hospital

    TERMINATED

    Auchenflower, Queensland, 4066, Australia

  • Therapeutic Concepts

    COMPLETED

    Houston, Texas, 77004, United States

  • UCLA

    ACTIVE_NOT_RECRUITING

    Los Angeles, California, 90024, United States

  • UT Southwestern Medical Center

    RECRUITING

    Dallas, Texas, 75390, United States

  • University of California Davis Health System

    RECRUITING

    Sacramento, California, 95817, United States

    Contact

    Contact

  • University of California San Diego Medical Center

    WITHDRAWN

    San Diego, California, 92093, United States

  • University of Chicago

    WITHDRAWN

    Chicago, Illinois, 60637, United States

  • University of Cincinnati

    WITHDRAWN

    Cincinnati, Ohio, 45267, United States

  • University of Iowa Health Care

    RECRUITING

    Iowa City, Iowa, 52242, United States

  • University of Kansas Medical Center

    RECRUITING

    Fairway, Kansas, 66205, United States

  • University of Maryland

    WITHDRAWN

    Baltimore, Maryland, 21201, United States

  • University of Nebraska Medical Center

    WITHDRAWN

    Omaha, Nebraska, 68198, United States

  • University of Oklahoma Health Sciences Center

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • University of Pennsylvania

    WITHDRAWN

    Philadelphia, Pennsylvania, 19104, United States

  • University of Pittsburgh Medical Center Health System

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

  • Universtiy of Michigan

    WITHDRAWN

    Ann Arbor, Michigan, 48109, United States

  • VCU Health System

    RECRUITING

    Richmond, Virginia, 23298, United States

    Contact

    Contact

  • Vanderbilt University Medical Center

    WITHDRAWN

    Nashville, Tennessee, 37232, United States

  • Washington University

    WITHDRAWN

    St Louis, Missouri, 63112, United States

  • Weill Cornell Medical College

    RECRUITING

    New York, New York, 10065, United States

    Contact

    Contact

  • West China Hospital

    TERMINATED

    Chengdu, Sichuan, 610041, China

  • Westmead Hospital

    TERMINATED

    Sydney, New South Wales, 2145, Australia

Conditions

Explore the condition pages connected to this study.