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New pill could replace shots for prostate cancer treatment

NCT ID NCT02972060

First seen Nov 01, 2025 · Last updated May 18, 2026 · Updated 37 times

Summary

This study compares an experimental oral drug, darolutamide, to standard hormone therapy (injections) for men with prostate cancer that still responds to hormones. About 250 men with early-stage or limited metastatic disease will be randomly assigned to one of the two treatments. The main goal is to see if the pill can lower PSA levels as effectively as the injections after 24 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Azienda Ospedaliera Citta della Salute e della Scienza di Torino - Ospedale Molinette

    Torino, 10126, Italy

  • CHU Dinant Godinne - UCL Namur

    Yvoir, 5530, Belgium

  • CHU de Dijon - Centre Georges-Francois-Leclerc

    Dijon, 21079, France

  • Cliniques Universitaires Saint-Luc

    Brussels, 1200, Belgium

  • Fundacion Instituto Valenciano De Oncologia

    Valencia, 46009, Spain

  • Gustave Roussy

    Villejuif, 94805, France

  • Hopitaux Universitaires Bordet-Erasme - Hopital Universitaire Erasme

    Brussels, 1070, Belgium

  • Hospital Universitario Ramon y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Virgen De La Victoria

    Málaga, 29010, Spain

  • Hospital Universitario de Salamanca

    Salamanca, 37007, Spain

  • Institut Catala d'Oncologia - ICO Badalona - Hospital Germans Trias i Pujol

    Badalona, 08916, Spain

  • Universitair Ziekenhuis Gent

    Ghent, 9000, Belgium

Conditions

Explore the condition pages connected to this study.