Which blood thinner is safer for heart patients with low platelets?
NCT ID NCT06223607
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 300 adults with low platelet counts who need a heart stent. It compares two common blood thinner combinations (aspirin plus clopidogrel vs. aspirin plus ticagrelor) to see which causes fewer bleeding problems. The goal is to find the safer option for these patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2022
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Study population of 18 years of age ,PCI with either DES or BMS during study time period (April 1, 2018 through July 1 2021) ,Thrombocytopenia on at least one occasion prior to PCI and at least one dose of DAPT post-PCI with aspirin and either clopidogrel or ticagrelor
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * ≥ 18 years * PCI with either DES or BMS during study time period (April 1, 2018 through July 1 2021) * Thrombocytopenia defined as platelet count \<100 x103 /µL on at least one occasion prior to PCI * At least one dose of DAPT post-PCI with aspirin and either clopidogrel or ticagrelor Exclusion Criteria: * Death within 48 hours post-PCI * DAPT prior to cardiac catheterization
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Methodist Dallas Medical Center
RECRUITINGDallas, Texas, 75203, United States