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New combo therapy may keep melanoma from coming back after surgery

NCT ID NCT04666272

First seen Feb 21, 2026 · Last updated May 23, 2026 · Updated 15 times

Summary

This study looks at whether taking two drugs, dabrafenib and trametinib, after surgery can help prevent melanoma from returning in Chinese patients with a specific gene change (BRAF V600). The treatment is given to people with stage III melanoma that has been completely removed. The main goal is to see how long patients stay cancer-free after starting the drugs.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Fuzhou, Fujian, 350014, China

  • Novartis Investigative Site

    Zhengzhou, Henan, 410100, China

  • Novartis Investigative Site

    Wuhan, Hubei, 430022, China

  • Novartis Investigative Site

    Changsha, Hunan, 410013, China

  • Novartis Investigative Site

    Nanjing, Jiangsu, 210008, China

  • Novartis Investigative Site

    Kunming, Yunnan, 650106, China

  • Novartis Investigative Site

    Hangzhou, Zhejiang, 310022, China

  • Novartis Investigative Site

    Beijing, 100036, China

Conditions

Explore the condition pages connected to this study.