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Can cyclosporine eye drops tame severe eye allergies in kids?

NCT ID NCT07732855

Disease control Sponsor: Semmelweis University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 29, 2026 · Last updated Aug 04, 2026 · Updated 3 times

Summary

This trial tests whether cyclosporine 1% eye drops can help children with severe allergic eye inflammation. The main goal is to see if the drops reduce the need for rescue steroid treatments. Participants will use the eye drops daily for months and track their symptoms and steroid use during regular clinic visits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
cyclosporine 1% eye drops
What this could lead to
If effective, this could offer a steroid-sparing option for managing severe allergic eye inflammation in children.
What could go wrong
This is a small, early-stage trial with 50 participants. The treatment may not reduce steroid use significantly, and side effects like eye irritation are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2025

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with chronic ocular surface inflammation are involved and followed. Patients older than 4 years and younger than 60 years are involved. Women and men are involved , all types of rasses are involved.

Ages

4 to 60 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * ocular surface inflammatory disease cornea inflammation -keratitis Exclusion Criteria: * eye surgery within 1 year, lack of fitness for the objective ocular surface measurments

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Conditions

The condition(s) this trial relates to.

atopic conjunctivitis blepharoconjunctivitis Conjunctivitis, Allergic eye allergy keratitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Blepharoconjunctivitis Conjunctivitis, allergic Ocular surface allergy

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Semmelweis University Department of Ophthalmology

    RECRUITING

    Budapest, Pest County, 1085, Hungary

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