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Leg vein problems may slow recovery after knee surgery

NCT ID NCT07577141

Knowledge-focused Sponsor: SB Istanbul Education and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will follow 100 people getting a total knee replacement to see if those with chronic venous insufficiency (poor blood flow in leg veins) have more wound healing problems. Participants will have an ultrasound before surgery to check their veins and then be monitored for a year. The goal is to learn whether vein health should be a routine part of pre-surgery risk assessment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds a clear link, doctors could better identify patients at risk for wound problems before knee replacement surgery.
What could go wrong
This is an observational study, not a treatment trial. It will not test any new drug or procedure, so it cannot directly improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Total Knee Arthroplasty patients

Ages

50 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing primary total knee arthroplasty * Age ≥ 50 years * Ability to provide informed consent Exclusion Criteria: * Revision TKA * Peripheral arterial disease (ABI \< 0.9) * Active infection * History of deep vein thrombosis within 6 months * Immunosuppressive therapy * Severe uncontrolled diabetes mellitus

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Conditions

The condition(s) this trial relates to.

chronic venous insufficiency injury osteoarthritis, knee venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Doppler ultrasound diagnosis Total knee anthroplasty Venous insufficiency (chronic)(peripheral)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

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Other studies related to the condition(s) this trial covers.