Could your socks cure foot pain? new trial tests custom 3D-Printed inserts
NCT ID NCT06534073
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether custom-designed socks with built-in 3D-printed supports can reduce pain from metatarsalgia, a common cause of forefoot pain in older women. 180 women over 55 will wear either the special socks, custom insoles, or a removable toe aligner for six months. Researchers will measure pain, quality of life, and activity levels to see if the socks work as well or better than standard treatments.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- custom 3D-printed plantar offloading elements integrated into socks
- What this could lead to
- If it works, this could offer a simple, personalized sock that reduces foot pain without needing special insoles or devices.
- What could go wrong
- This is an early-stage trial with only 180 women over 55, so results may not apply to everyone. The custom socks might not relieve pain better than existing treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 180 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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55 years and older
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female sex; * Age ≥ 55 years; * Experiencing moderate to severe pain in the plantar area of the forefoot; * Presenting hyperkeratosis under the central metatarsal heads; * Presenting pre-dislocation syndrome of the second or third metatarsophalangeal joint. Exclusion Criteria: * Present cognitive deterioration that impedes the proper development of the study; * Have undergone previous osteoarticular surgeries on the feet; * Diagnosis of rheumatoid arthritis with involvement in the metatarsophalangeal joints of the foot; * Present symptoms compatible with Morton's neuritis; * Use of walking aids; * Are under treatment with insoles; * Refuse the use of designated socks or plantar supports during the follow-up period.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Facultad de Enfermería, Fisioterapia y Podología
Seville, Seville, 41008, Spain
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Other studies related to the condition(s) this trial covers.