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New drug CTX-8371 enters first human tests for multiple advanced cancers

NCT ID NCT06150664

First seen Jan 05, 2026 · Last updated Apr 30, 2026 · Updated 12 times

Summary

This early-stage study tests the safety of a new drug called CTX-8371 in people with advanced cancers (lung, breast, lymphoma, head & neck, or melanoma) that have not responded to standard treatments. About 85 participants will receive increasing doses of the drug to find the safest dose and check for side effects. The goal is to see if the drug can control the disease and determine doses for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact

    Contact Email: •••••@•••••

  • D&H Cancer Research Center

    WITHDRAWN

    Margate, Florida, 33063, United States

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Florida Cancer Specialists - Lake Nona

    RECRUITING

    Orlando, Florida, 32827, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Florida Cancer Specialists - Sarasota

    RECRUITING

    Sarasota, Florida, 34236, United States

    Contact

  • Roswell Park Cancer Institute

    RECRUITING

    Buffalo, New York, 14263, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Summit Cancer Center

    RECRUITING

    Spokane, Washington, 99208, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tennessee Oncology

    RECRUITING

    Nashville, Tennessee, 37203, United States

    Contact

    Contact Email: •••••@•••••

  • University Cancer & Blood Center

    RECRUITING

    Athens, Georgia, 30607, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.