Blood test may spot hidden HPV cancers before symptoms show

NCT ID NCT03739775

Ongoing Diagnosis Sponsor: Institut Curie Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 36 times

Summary

This study looks at whether a simple blood test that finds tiny bits of tumor DNA (ctDNA) can detect the return of HPV-positive pelvic cancers (like cervical or anal cancer) earlier than usual scans or exams. About 172 people who have already been treated for these cancers and are currently cancer-free will give blood samples. Researchers will check if a high level of ctDNA in the blood can predict a relapse within the next 6 months.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

CHU Pontchaillou

Rennes, 35033, France
CHU de Besançon

Besançon, 25030, France
Hôpital Tenon

Paris, 75020, France
Institut Curie - Paris

Paris, 75005, France
Institut Curie - Saint-Cloud

Saint-Cloud, 92210, France

Conditions

The condition(s) this trial relates to.

anal canal cancer cervical carcinoma human papillomavirus-related penile squamous cell carcinoma vaginal carcinoma vulvar carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HPV POSITIVE PELVIC CANCER