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Blood test may reveal early if lung cancer therapy works

NCT ID NCT03926260

First seen Jan 11, 2026 · Last updated Jun 21, 2026 · Updated 26 times

Summary

This study looked at whether changes in tumor DNA found in the blood (ctDNA) can help doctors know early if treatment is working for people with advanced lung cancer. Researchers took blood samples from 100 patients before treatment and again at 3 and 9 weeks. The goal was to see if ctDNA levels rising or falling matched with tumor shrinkage or growth on scans. If validated, this approach could allow faster treatment adjustments without waiting for standard imaging.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Jaafar BENNOUNA

    Nantes, 44000, France

  • Marie MARCQ

    La Roche-sur-Yon, 85000, France

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test to quickly tell if lung cancer treatment is working, helping doctors adjust therapy sooner.

What could go wrong

This is a small pilot study, not a treatment trial. The test may not reliably predict outcomes in all patients, and more research is needed before it can be used in practice.

Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.