DNA-Guided drug switch could improve GIST outcomes
NCT ID NCT05366816
First seen Nov 01, 2025 · Last updated May 18, 2026 · Updated 32 times
Summary
This study tests whether DNA changes in the KIT gene can help doctors choose the right drug for people with advanced gastrointestinal stromal tumor (GIST). About 48 adults who have already tried imatinib will receive either sunitinib or regorafenib based on their tumor's DNA. The goal is to see if this personalized approach improves response rates and delays disease progression.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
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Contact
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Locations
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University of Miami
RECRUITINGMiami, Florida, 33136, United States
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Contact
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