Can a CT-Free navigation system pinpoint lung nodules with precision?
NCT ID NCT07743775
First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time
Summary
This study is testing whether a CT-free electromagnetic navigation system can accurately locate small lung nodules before surgery, compared to the standard CT-guided method. The goal is to see if the new approach can mark nodules within 10 millimeters of their center, which is crucial for successful removal. Researchers will also compare procedure time, complications, and recovery. The study involves adults with non-palpable pulmonary nodules who need sublobar resection.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- CT-Free electromagnetic navigation percutaneous localization system
- What this could lead to
- If successful, this could offer a safer, faster, and more accurate way to mark lung nodules before surgery, potentially reducing the need for repeated CT scans and improving surgical outcomes.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The new method may not be as accurate or safe as standard CT-guided localization, and results may vary across different centers.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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153 people
The number who actually took part.
- Started
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Jun 2025
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with pulmonary nodules requiring preoperative localization before sublobar lung resection at multiple participating centers.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Adults aged 18 years or older. 2. Patients with pulmonary nodules requiring sublobar resection. 3. Non-palpable pulmonary nodules requiring preoperative localization. 4. Patients undergoing CT-Free electromagnetic navigation localization or CT-guided localization. Exclusion Criteria: 1. Central pulmonary nodules unsuitable for localization. 2. Patients unable to undergo sublobar resection. 3. Patients with severe cardiopulmonary dysfunction or major organ dysfunction. 4. Pregnancy or breastfeeding. 5. Patients participating in other clinical trials.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Nantong First People's Hospital
Nantong, Jiangsu, China
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Nantong Sixth People's Hospital
Nantong, Jiangsu, China
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Nantong University Affiliated Hospital
Nantong, Jiangsu, China
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Other studies related to the condition(s) this trial covers.
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